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About DEFRANKS

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DEFRANKS has contributed 628 entries to our website, so far.

1STEPS AREN’T ENOUGH. What 70-Year-Olds With YOUNG Mitochondria Do Instead

STEPS AREN’T ENOUGH. What 70-Year-Olds With YOUNG Mitochondria Do Instead

Sep 5, 2026

10,000 steps a day has been THE number for what feels like a good two decades now. The activity sweet spot that checks all the biological boxes to outpace that buzzkill, the Grim Reaper. The number that makes YOUR chronological number hit the brakes. And of course, equilibrium that decides whether you’ve earned your evening […]

23 Minutes of Sprinting BETTER THAN 90 Minutes of Cardio? (New Study)

3 Minutes of Sprinting BETTER THAN 90 Minutes of Cardio? (New Study)

Aug 29, 2026

You know what they say… why spend 90 minutes on something you can do in three, right? Well, this might be the best news you’ve heard all week. New research out of Rockefeller University just compared the proteomic and metabolomic response (aka the proteins and metabolites circulating in your blood) of short all-out bursts versus […]

3NEW Glymphatic Science: Exercise Boosts Your Brain’s Nightly Clean – HERE’S MY ROUTINE

NEW Glymphatic Science: Exercise Boosts Your Brain’s Nightly Clean – HERE’S MY ROUTINE

Aug 22, 2026

In a weird twist of evolutionary fate, your brain doesn’t have a lymphatic system, aka that vast network of vessels and nodes that collects and removes cellular crap throughout the rest of your body. Which yes, means every other organ gets an elaborate plumbing network to haul out the trash, while the brain gets a […]

4I Fasted 40 Hours — 3 Blood Markers Did Something Unexpected

I Fasted 40 Hours — 3 Blood Markers Did Something Unexpected

Aug 15, 2026

You’re Not a Textbook Human. None of us are. We’re all out in the wild, throwing hundreds of variables at our bodies every day. So no, it doesn’t make sense to expect everyone’s blood work to land in the same exact range. I mean, they call them “reference ranges” for a reason. So the sooner […]

5Can Your LEG MUSCLE Predict BRAIN DECLINE?

Can Your LEG MUSCLE Predict BRAIN DECLINE?

Aug 8, 2026

A lot can happen in ten years. Which makes seeing into the future, especially when it comes to your one and only pretty cool meat, a pretty valuable edge. I mean, I would almost guarantee that if someone handed you your exact health status a decade from now, you’d surely change some of your present-day […]

6SITTING IS NOT the NEW SMOKING | Here’s the Truth

SITTING IS NOT the NEW SMOKING | Here’s the Truth

Aug 1, 2026

If you haven’t been living under a rock for the last decade, you’ve probably heard that sitting is the new smoking. The “new” publicly accepted, enjoyable, everyday lifestyle habit that feels ever so relaxing while you’re doing it, yet is secretly deteriorating your health from the inside out. Kinda hard to believe, right? Well, for […]

765-Year-Olds With the Mitochondria of 25-Year-Olds — Here’s Their SECRET

65-Year-Olds With the Mitochondria of 25-Year-Olds — Here’s Their SECRET

Jul 25, 2026

Getting younger at the cellular level is a pretty cool idea. But for now, that’s where it stops — as an idea. That said, a more youthful molecular expression, appearance, and function of your key cellular components — compared to same-aged peers — IS a Real Thing. A thing we in the biz call preserving […]

8How I Keep My Testosterone at 1000 ng/dL in My 30s

How I Keep My Testosterone at 1000 ng/dL in My 30s

Jul 18, 2026

We’re told a guy’s testosterone drops 1 to 2 percent a year once we hit 30. It’s supposed to ghost you. Leave you on read. Slip out the back in the middle of the party. But for some reason, mine’s doing the opposite. Well — actually, there may be a few reasons. Turns out testosterone […]

9You Can’t Fix Your Fatty Liver Without Fixing Your…

You Can’t Fix Your Fatty Liver Without Fixing Your…

Jul 11, 2026

If you weren’t aware, your liver is the unsung workhorse that keeps your whole body running. Not only does it synthesize the critical compounds that hold your metabolic balance together around the clock — it’s also the first-pass filter for everything absorbed through your gut, breaking down nutrients and toxins alike. Which means the health […]

10Can GLP-1’s REALLY SLOW Biological Aging: NEW RESEARCH

Can GLP-1’s REALLY SLOW Biological Aging: NEW RESEARCH

Jul 4, 2026

Well, I hate to say it, but “there’s a pill for that” seems to be getting closer by the day. Which, coming from a “lifestyle is the ultimate longevity lever” enthusiast, is a tough pill to swallow — pun intended, of course. But we may have more time than we think. Because while new data […]

11Sleep More, Eat Less: 270 Fewer Calories a Day?

Sleep More, Eat Less: 270 Fewer Calories a Day?

Jun 27, 2026

You might assume that sleeping more helps you eat less for the obvious reason: fewer waking hours means fewer hours to eat. Simple Math, right? Couldn’t be further from the truth. In reality, consistent high-quality sleep acts as a governor on your entire hunger, craving, and appetite apparatus — regulating the delicate balance of neurochemical, […]

12The Exercise + Sleep Combo That Fixes Restless Nights

The Exercise + Sleep Combo That Fixes Restless Nights

Jun 19, 2026

The 2am wake-up — where you snap awake for no reason and immediately begin re-litigating every decision you’ve ever made. A tradition like no other. Clinically known as sleep fragmentation, and it’s not some rare glitch: more than a third of adults pull this exact move at least three nights a week. But the part […]

13What Creatine Does to an Aging Body & Brain | NEW RCT

What Creatine Does to an Aging Body & Brain | NEW RCT

Jun 13, 2026

Despite being one of the most studied supplements ever, hearing the word creatine and not immediately thinking about muscle is almost unfathomable. Because this legendary white powder has been a hallmark of pushing our physical limits for what feels like forever. It’s secret being behind enhancing cellular energy recycling — letting cells replenish their fuel […]

14Coronary Calcium Score: The Surprising NEW Fasting & Gut Bacteria Connection

Coronary Calcium Score: The Surprising NEW Fasting & Gut Bacteria Connection

Jun 6, 2026

If I asked you about clogged arteries, the first thing that pops into your head is probably cholesterol. A few of you might even mention that calcium scan you got — or that test which measures calcified plaque and your risk of a heart attack. But I can almost guarantee no one, not even the […]

15You’re Not Tougher Than Sleep – And Changes to Your DNA Methylation Prove it

You’re Not Tougher Than Sleep – And Changes to Your DNA Methylation Prove it

May 30, 2026

When you think about it, spending roughly 7 of every 24 hours in a state of pure unconsciousness is kinda silly. Not just from a time-management standpoint, but from an evolutionary survival one. Rewind a few thousand years, before comfy homes and locked doors, we (well, the tribe) slept out in the elements for thousands […]

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  • STEPS AREN’T ENOUGH. What 70-Year-Olds With YOUNG Mitochondria Do Instead
  • 3 Minutes of Sprinting BETTER THAN 90 Minutes of Cardio? (New Study)
  • NEW Glymphatic Science: Exercise Boosts Your Brain’s Nightly Clean – HERE’S MY ROUTINE
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  • Can Your LEG MUSCLE Predict BRAIN DECLINE?

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